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RXinsider • Jan 02, 2019

Closed-System Transfer Devices (CSTDs) | A comparison of CSTD manufacturers.

The following comparison matrix was developed as a complimentary service for anyone in the beginning stages of research. Due to USP 800 becoming enforceable in December 2019, CSTDs will be required for hazardous drug administration and recommended for hazardous drug preparation.


Every component creates an audible "click" sound when attached correctly. | First CSTD cleared under ONB product code. First completely sealed drug delivery system. Mechanically prohibits the escape of hazardous drug, vapor, or aerosols. Ensures leakproof drug transfer thanks to elastomeric, double membranes; has a sealed expansion chamber that captures and retains hazardous drugs. | For Alaris™ pump customers, the Texium system components can be integrated into the administration sets to aid in workflow and prevent accidental disconnections to the infusion line. | Only CSTD without an internal or external vent, valve, or filter, which maximizes drug extraction using six simple pieces. Designed especially to protect the healthcare worker. | Fully encapsulated syringe barrel serving as a pressure equalization chamber, preventing plunger rod contamination and preventing accidental removal of plunger from the back of the syringe. | Needle-free and easy-to-use. Requires no assembly of components at the bedside and includes bonded and locking mechanisms that ensure compliance. For example the secondary administration sets incorporate the CSTD bonded to the set to create a nonremovable connection to prevent accidental disconnect. | First needle-free CSTD to receive FDA clearance. A system with a wider fluid path that requires less push-pull forces than needle CSTD systems. Does not increase the risk of repetitive stress injuries. | Features an intravenous dry spike that helps provide closed access to an IV bag for addition and removal of a drug or solution. No need to inject air into the vial.



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